Publications: 2005-2007

Publications: 2003-2004

Publications: 2000-2002

Publications: 1997-1999

Pubs by Keyword

Pubs by First Author





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Copyright © 2004-2007 Massachusetts General Hospital
 
The following is a listing of publications that appeared from January 1, 2000 through the end of 2002.

2002

Alcoholic pancreatitis in rats: injury from nonoxidative metabolites of ethanol
Werner J, Saghir M, Warshaw AL, Lewandrowski KB, Laposata M, Iozzo RV, Carter EA, Schatz RJ, Fernandez-Del Castillo C. Am J Physiol Gastrointest Liver Physiol. 283:G65-73, 2002

The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD
Spiller MP, Kambadur R, Jeanplong F, Thomas M, Martyn JK, Bass JJ, Sharma M. Mol Cell Biol.
22:7066-82, 2002

Mechanism of suppression of insulin signaling with lignocaine
Hirose M, Martyn JA, Kuroda Y, Marunaka Y, Tanaka Y. Br J Pharmacol. 136:76-80, 2002

Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance
Sugita H, Kaneki M, Tokunaga E, Sugita M, Koike C, Yasuhara S, Tompkins RG, Martyn JA. Am J Physiol Endocrinol Metab. 282:E386-94, 2002

Homocysteine impairs coronary microvascular dilator function in humans
Tawakol A, Forgione MA, Stuehlinger M, Alpert NM, Cooke JP, Loscalzo J, Fischman AJ, Creager MA, Gewirtz H. J Am Coll Cardiol. 40:1051-58, 2002

Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H215O
Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM. J Appl Physiol 92:1709-16, 2002

Mapping of local renal blood flow with PET and H215O
Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ. J Nucl Med 43:470-5, 2002

Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans
Yu YM, Ryan CM, Fei ZW, Lu XM, Castillo L, Schulz JT, Tompkins RG, Young VR. American Journal of Physiology-Endocrinology & Metabolism. 282:E247-58, 2002

Long-term consequences of toxic epidermal necrolysis in children
Sheridan RL, Schulz JT, Ryan CM, Schnitzer JJ, Lawlor D, Driscoll DN, Donelan MB, and Tompkins RG. Pediatrics. 109:74-8, 2002

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2001

The p70 S6 kinase integrates nutrient and growth signals to control translational capacity
Avruch J, Belham C, Weng Q, Hara K, Yonezawa K. Prog Mol Subcell Biol. 2001;26:115-54

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
Kyriakis JM, Avruch J. Physiol Rev. 2001 Apr;81(2):807-69

Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade
Avruch J, Khokhlatchev A, Kyriakis JM, Luo Z, Tzivion G, Vavvas D, Zhang XF. Recent Prog Horm Res. 2001;56:127-55

Daily requirement for and splanchnic uptake of leucine in healthy adult Indians
Kurpad AV, Raj T, El-Khoury A, Kuriyan R, Maruthy K, Borgonha S, Chandukudlu D, Regan MM, Young VR. Am J Clin Nutr. 74(6):747-55, 2001

Presidential Address - The American Burn Association in the New Millennium
Tompkins RG. J Burn Care Rehabil. 22:369-374, 2001

Got some amino acids to spare?
Young VR. Am J Clin Nutr. 74:709-11, 2001

Disparate dysfunction of skeletal muscles located near and distant from burn site in the rat.
Ibebunjo C. Martyn J. Muscle & Nerve. 24(10):1283-94, 2001 Oct

Glutamine: the emperor or his clothes?
Young VR, Ajami AM. J Nutr 131(9 Suppl):2449S-59S, 2001

Initial experience with a composite autologous skin substitute
Sheridan RL, Morgan JR, Cusick JL, Petras LM, Lydon MM, Tompkins RG. Burns. 27 :421-4, 2001

Lysine requirements of healthy adult Indian subjects, measured by an indicator amino acid balance technique
Kurpad AV, Raj T, El-Khoury A, Beaumier L, Kuriyan R, Srivatsa A, Borgonha S, Selvaraj A, Regan MM, Young VR. Am J Clin Nutr. 73:900-7, 2001

Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients
Lyons J, Rauh-Pfeiffer A, Ming-Yu Y, Lu XM, Zurakowski D, Curley M, Collier S, Duggan C, Nurko S, Thompson J, Ajami A, Borgonha S, Young VR, Castillo L. Crit Care Med. 29:870-7, 2001

Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal
Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR. Am J Physiol Endocrinol Metab. 280:E509-17, 2001

Metabolism 2000: the emperor needs new clothes
Young VR, Ajami AM. Proc Nutr Soc. 60:27-44, 2001

Long-term denervation impairs insulin receptor substrate-1-mediated insulin signaling in skeletal muscle
Hirose M, Kaneki M, Sugita H, Yasuhara S, Ibebunjo C, Martyn JA, Iebunjo C. Metabolism. 50:216-22, 2001

Asparagine uptake in rat hepatocytes: resolution of a paradox and insights into substrate-dependent transporter regulation
Pawlik TM, Souba WW, Bode BP. Amino Acids. 20:335-52, 2001

Immobilization depresses insulin signaling in skeletal muscle
Hirose M, Kaneki M, Sugita H, Yasuhara S, Martyn JA. Am J Physiol Endocrinol Metab. 279:E1235-41, 2001

Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals
Yasuhara S, Perez ME, Kanakubo E, Yasuhara Y, Shin YS, Kaneki M, Fujita T, Martyn JA. Am J Physiol Endocrinol Metab. 279:E1114-21, 2001

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2000

Nuclear DNA fragmentation and morphological alterations in adult rabbit skeletal muscle after short-term immobilization
Smith HK, Maxwell L, Martyn JA, Bass JJ. Cell Tissue Res. 302:235-41, 2000

Thermal injury induces greater resistance to d-tubocurarine in local rather than in distant muscles in the rat
Ibebunjo C, Martyn JA. Anesth Analg. 91:1243-9, 2000

Prednisolone-induced muscle dysfunction is caused more by atrophy than by altered acetylcholine receptor expression
Shin YS, Fink H, Khiroya R, Ibebunjo C, Martyn J. Anesth Analg. 91:322-8, 2000

Plants and animals share functionally common bacterial virulence factors
Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG. Proc Natl Acad Sci U S A. 97:8815-21, 2000

Twenty-four-hour oral tracer studies with L-[1-13C]lysine at a low (15 mg • kg-1 • d-1) and intermediate (29 mg • kg-1 • d-1) lysine intake in healthy adults
El-Khoury AE, Pereira PC, Borgonha S, Basile-Filho A, Beaumier L, Wang SY, Metges CC, Ajami AM, Young VR. Am J Clin Nutr. 72:122-30, 2000

Nitrogen and amino acid requirements: the Massachusetts Institute of Technology amino acid requirement pattern
Young VR, Borgonha S. J Nutr. 130:1841S-9S, 2000

Kinetics of L-[1-13C]leucine when ingested with free amino acids, unlabeled or intrinsically labeled casein
Metges CC, El-Khoury AE, Selvaraj AB, Tsay RH, Atkinson A, Regan MM, Bequette BJ, Young VR. Am J Physiol Endocrinol Metab. 278:E1000-9, 2000

Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet
Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L. Proc Natl Acad Sci U S A. 97:5071-6, 2000

Arginine, citrulline, and nitric oxide metabolism in end-stage renal disease patients
Lau T, Owen W, Yu YM, Noviski N, Lyons J, Zurakowski D, Tsay R, Ajami A, Young VR, Castillo L. J Clin Invest. 105:1217-25, 2000

Oxoproline kinetics and oxoproline urinary excretion during glycine- or sulfur amino acid-free diets in humans
Metges CC, Yu YM, Cai W, Lu XM, Wong S, Regan MM, Ajami A, Young VR. Am J Physiol Endocrinol Metab. 278:E868-76, 2000

Inverse relationship between protein intake and plasma free amino acids in healthy men at physical exercise
Forslund AH, Hambraeus L, van Beurden H, Holmback U, El-Khoury AE, Hjorth G, Olsson R, Stridsberg M, Wide L, Akerfeldt T, Regan M, Young VR. Am J Physiol Endocrinol Metab. 278:E857-67, 2000

Hepatic glutamine transporter activation in burn injury: role of amino acids and phosphatidylinositol-3-kinase
Pawlik TM, Lohmann R, Souba WW, Bode BP. Am J Physiol 278:G532-41, 2000

Glutamate: an amino acid of particular distinction
Young VR, Ajami AM. J Nutr. 130(4S Suppl):892S-900S, 2000

Rates of urea production and hydrolysis and leucine oxidation change linearly over widely varying protein intakes in healthy adults
Young VR, El-Khoury AE, Raguso CA, Forslund AH, Hambraeus L. J Nutr. 130:761-6, 2000

Artificial skin
Schulz JT 3rd, Tompkins RG, Burke JF. Annu Rev Med. 51:231-44, 2000

Trends in tracer techniques, including use of positron emission tomography
Young VR, Borgonha S, Ajami AM. Diabetes Nutr Metab. 13:35-45, 2000

Cysteine kinetics and oxidation at different intakes of methionine and cysteine in young adults
Raguso CA, Regan MM, Young VR. Am J Clin Nutr. 71:491-9, 2000

Proteins, peptides and amino acids in enteral nutrition: overview and some research challenges
Young VR, Yu YM, Borgonha S. Nestle Nutr Workshop Ser Clin Perform Programme. 3:1-20; discussion 20-3, 2000

Long-term outcome of children surviving massive burns
Sheridan RL, Hinson MI, Liang MH, Nackel AF, Schoenfeld DA, Ryan CM, Mulligan JL, Tompkins RG. JAMA 283:69-73, 2000

Neuromuscular effects of mivacurium in 2- to 12-yr-old children with burn injury
Martyn JA, Goudsouzian NG, Chang Y, Szyfelbein SK, Schwartz AE, Patel SS. Anesthesiology. 92:31-7, 2000

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