The following is a listing of papers published by The MGH Burn Research Center from January 1, 2003 through December 31, 2004:

2004

Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication
Deziel E, Lepine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1339-44

What's new in burns and metabolism?
Sheridan RL, Tompkins RG. J Am Coll Surg. 2004 Feb;198(2):243-63

Support of the metabolic response to burn injury
Herndon DN, Tompkins RG. Lancet 2004 Jun 5;363(9424):1895-902

Introduction to the 3rd Amino Acid Assessment Workshop
Cynober L, Young VR. J Nutr. 2004 Jun;134(6 Suppl):1555S-1557S

Daily requirement for total sulfur amino acids of chronically undernourished Indian men
Kurpad AV, Regan MM, Varalakshmi S, Gnanou J, Young VR. Am J Clin Nutr. 2004 Jul;80(1):95-100

Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study
Sheridan RL, Prelack K, Yu YM, Lydon M, Petras L, Young VR, Tompkins RG. Surgery. 2004 Jun;135(6):671-8

L-arginine transport in the human coronary and peripheral circulation
Miner SE, Al-Hesayen A, Kelly S, Benson T, Thiessen JJ, Young VR, Parker JD. Circulation. 2004 Mar 16;109(10):1278-83. Epub 2004 Mar 08

Synthesis of a macromolecular camptothecin conjugate with dual phase drug release
Yurkovetskiy AV. Hiller A. Syed S. Yin M. Lu XM. Fischman AJ. Papisov MI.
Mol Pharm. 1(5):375-82, 2004 Sep-Oct.

Does whole-body 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography have an advantage over thoracic positron emission tomography for staging patients with lung cancer?
Aquino SL, Fischman AJ. Chest. 2004 Sep;126(3):755-60

Preparation and pharmacokinetics of 11C labeled stavudine (d4T)
Livni E, Berker M, Hillier S, Waller SC, Ogan MD, Discordia RP, Rienhart JK, Rubin RH, Fischman AJ. Nucl Med Biol. 2004 Jul;31(5):613-21

Hippocampal function in posttraumatic stress disorder
Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, Lasko N, Segal E, Makris N, Richert K, Levering J, Schacter DL, Alpert NM, Fischman AJ, Pitman RK, Rauch SL. Hippocampus. 2004;14(3):292-300

Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue
Carter EA, Burks D, Fischman AJ, White M, Tompkins RG. Int J Mol Med. 2004 Oct;14(4):653-8

Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
Praskova M, Khoklatchev A, Ortiz-Vega S, Avruch J. Biochem J. 2004 Jul 15;381(Pt 2):453-62

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death
Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B. J Biol Chem. 2004 Jul 9;279(28):29247-54

Steroidal nondepolarizing muscle relaxants do not simulate the effects of glucocorticoids on glucocorticoid receptor-mediated transcription in cultured skeletal muscle cells
Yasukawa T, Kaneki M, Yasuhara S, Lee SL, Martyn JA. Anesthesiology. 2004 Jun;100(6):1615-9

Neuromuscular pharmacodynamics of rocuronium in patients with major burns
Han T, Kim H, Bae J, Kim K, Martyn JA. Anesth Analg. 2004 Aug;99(2):386-92

Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model
Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML. Liver Transpl. 2004; 10(2):264-72

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2003

Intestinal parasites increase the dietary lysine requirement in chronically undernourished Indian men
Kurpad AV, Regan MM, Nazareth D, Nagaraj S, Gnanou J, Young VR. Am J Clin Nutr. 2003 Dec;78(6):1145-51 (AA)

Daily methionine requirements of healthy Indian men, measured by a 24-h indicator amino acid oxidation and balance technique
Kurpad AV, Regan MM, Varalakshmi S, Vasudevan J, Gnanou J, Raj T, Young VR. Am J Clin Nutr. 2003 May;77(5):1198-205

What is apparent is not always real: lessons from lysine requirement studies in adult humans
Kurpad AV, Young VR. J Nutr. 2003 Apr;133(4):1227-30

Leucine requirement and splanchnic uptake of leucine in chronically undernourished adult Indian subjects
Kurpad AV, Regan MM, Raj T, Varalakshmi S, Gnanou J, Thankachan P, Young VR. Am J Clin Nutr. 2003 Apr;77(4):861-7

Sodium bromide by instrumental neutron activation analysis quantifies change in extracellular water space with wound closure in severely burned children
Prelack K, Sheridan R, Yu YM, Stamatelatos IE, Dwyer J, Dallal GE, Lydon M, Petras L, Kehayias JJ. Surgery. 2003 Apr;133(4):396-403

Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression
Dougherty DD, Weiss AP, Cosgrove GR, Alpert NM, Cassem EH, Nierenberg AA, Price BH, Mayberg HS, Fischman AJ, Rauch SL. J Neurosurg. 2003 Dec;99(6):1010-7

Who should read and interpret 18F-FDG PET studies?
Fischman AJ, Thrall JH. J Nucl Med. 2003; 44(8):1197-9

A novel method for noninvasive detection of neuromodulatory changes in specific neurotransmitter systems
Alpert NM, Badgaiyan RD, Livni E, Fischman AJ. Neuroimage. 2003 Jul;19(3):1049-60

A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases
Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, Avruch J. J Biol Chem. 2003 Sep 12;278(37):34897-909

Apoptosis in critical illness
Lydon A, Martyn JA. Int Anesthesiol Clin. 41:65-77, 2003

Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptors
Fink H, Luppa P, Mayer B, Rosenbrock H, Metzger J, Martyn JA, Blobner M. Anesthesiology. 98 : 82-8, 2003

Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed states
Louis M, Poortmans JR, Francaux M, Hultman E, Berre J, Boisseau N, Young VR, Smith K, Meier-Augenstein W, Babraj JA, Waddell T, Rennie MJ. Am J Physiol 284 :E764-70, 2003

Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults
Rand WM, Pellett PL, Young VR. Am J Clin Nutr. 77:109-27, 2003

Id2 expression during apoptosis and satellite cell activation in unloaded and loaded quail skeletal muscles
Alway SE, Martyn JK, Ouyang J, Chaudhrai A, Murlasits ZS. Am J Physiol 284 :R540-9, 2003

In vivo rabbit hindquarter model for assessment of regional burn hypermetabolism
Xu J, Fei Z, Yu YM, Xu W, Rhodes A, Tompkins RG, Schulz JT. J Appl Physiol. 94 :135-40, 2003

Arginine and nitric oxide metabolism in critically ill septic pediatric patients
Argaman Z, Young VR, Noviski N, Castillo-Rosas L, Lu XM, Zurakowski D, Cooper M, Davison C, Tharakan JF, Ajami A, Castillo L. Crit Care Med. 31 :591-7, 2003

Myocardial flow regulation in people with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes/myoclonic epilepsy and ragged red fibers and other mitochondrial syndromes
Tawakol A, Sims K, MacRae C, Friedman JR, Alpert NM, Fischman AJ, Gewirtz H. Coron Artery Dis. 14 :197-205, 2003

Metabolic fate of extrahepatic arginine in liver after burn injury.
Chen CL. Fei Z. Carter EA. Lu XM. Hu RH. Young VR. Tompkins RG. Yu YM. Metabolism: Clinical & Experimental. 52(10):1232-9, 2003 Oct.

Central role of interleukin-6 in burn-induced stimulation of hepatic amino acid transport
Pawlik TM, Carter EA, Bode BP, Fischman AJ, Tompkins RG. Int J Mol Med. 2003 Oct;12(4):541-8

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