Publications: 2005-2007

Publications: 2003-2004

Publications: 2000-2002

Publications: 1997-1999

Pubs by Keyword

Pubs by First Author





Many of the papers in this section are available on PubMed. Click on the logo below for PubMed.























































































































































































Copyright © 2004-2007 Massachusetts General Hospital
 

The following is a listing of publications from 1997 through the present arranged alphabetically by first author, then by title. Most of them are available on PubMed. Click on the PubMed logo on the left side of the page to search for the publication by title.


A

Abcouwer SF, Lohmann R, Bode BP, Lustig RJ, Souba WW
Induction of glutamine synthetase expression after major burn injury is tissue specific and temporally variable
J Trauma. 42 :421-7; discussion 427-8, 1997

Alpert NM, Rabito CA, Correia DJ, Babich JW, Littman BH, Tompkins RG, Rubin NT, Rubin RH, Fischman AJ
Mapping of local renal blood flow with PET and H215O
J Nucl Med 43:470-5, 2002

Alpert NM, Badgaiyan RD, Livni E, Fischman AJ
A novel method for noninvasive detection of neuromodulatory changes in specific neurotransmitter systems
Neuroimage. 2003 Jul;19(3):1049-60

Alway SE, Martyn JK, Ouyang J, Chaudhrai A, Murlasits ZS
Id2 expression during apoptosis and satellite cell activation in unloaded and loaded quail skeletal muscles
Am J Physiol 284 :R540-9, 2003

Antoniewicz MR, Kelleher JK, Stephanopoulos G
Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements
Metab Eng. 8(4):324-37, 2006 Jul

Aquino SL, Fischman AJ
Does whole-body 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography have an advantage over thoracic positron emission tomography for staging patients with lung cancer?
Chest. 2004 Sep;126(3):755-60

Argaman Z, Young VR, Noviski N, Castillo-Rosas L, Lu XM, Zurakowski D, Cooper M, Davison C, Tharakan JF, Ajami A, Castillo L
Arginine and nitric oxide metabolism in critically ill septic pediatric patients
Crit Care Med. 31 :591-7, 2003

Astrakas LG, Goljer I, Yasuhara S, Padfield KE, Zhang Q, Gopalan S, Mindrinos MN, Dai G, Yu YM, Martyn JA, Tompkins RG, Rahme LG, Tzika AA
Proton NMR spectroscopy shows lipids accumulate in skeletal muscle in response to burn trauma-induced apoptosis
FASEB J. 19(11):1431-40, 2005 Sep

Avruch J, Belham C, Weng Q, Hara K, Yonezawa K
The p70 S6 kinase integrates nutrient and growth signals to control translational capacity
Prog Mol Subcell Biol. 2001;26:115-54

Avruch J, Khokhlatchev A, Kyriakis JM, Luo Z, Tzivion G, Vavvas D, Zhang XF
Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade
Recent Prog Horm Res. 2001;56:127-55


B

Babich JW, Tompkins RG, Graham W, Barrow SA, Fischman AJ
Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism
J Nucl Med. 38:1316-22, 1997

Basile-Filho A, Beaumier L, El-Khoury AE, Yu Y-M, Kenneway M, Gleason RE, Young VR
Twenty-four-hour L[1-13C]tyrosine and L-[3,3-2H2]phenylalanine oral tracer studies at generous, "requirement" and low phenylalanine intakes, to estimate aromatic amino acid requirement in adults
Am J Clin Nutr 67: 640-659, 1998

Beffa DC, Carter EA, Lu XM, Yu YM, Prelack K, Sheridan RL, Young VR, Fischman AJ, Tompkins RG.
Negative chemical ionization gas chromatography/mass spectrometry to quantify urinary 3-methylhistidine: application to burn injury
Anal Biochem. 355(1):95-101, 2006 Aug 1

Belham C, Roig J, Caldwell JA, Aoyama Y, Kemp BE, Comb M, Avruch J
A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases
J Biol Chem. 2003 Sep 12;278(37):34897-909


C

Carter EA
Insulin resistance in burns and trauma
Nutr Rev. 56 :S170-6, 1998

Carter EA, Burks D, Fischman AJ, White M, Tompkins RG
Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue
Int J Mol Med. 2004 Oct;14(4):653-8

Carter EA, Yu YM, Alpert NM, Bonab AA, Tompkins RG, Fischman AJ
Measurement of muscle protein synthesis by positron emission tomography with L-[methyl-11C]methionine: effects of transamination and transmethylation
J Trauma. 47 :341-5, 1999

Carter EA, Tompkins RG, Hsu H, Christian B, Alpert NM, Weise S, Fischman AJ
Metabolic alterations in muscle of thermally injured rabbits, measured by positron emission tomography
Life Sci. 61 :39-44, 1997

Chen CL, Fei Z, Carter EA, Lu XM. Hu RH, Young VR, Tompkins RG, Yu YM
Metabolic fate of extrahepatic arginine in liver after burn injury.
Metabolism: Clinical & Experimental. 52(10):1232-9, 2003 Oct

Cynober L, Young VR
Introduction to the 3rd Amino Acid Assessment Workshop
J Nutr. 2004 Jun;134(6 Suppl):1555S-1557S


D

Deziel E, Lepine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG
Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication
Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1339-44

Dougherty DD, Weiss AP, Cosgrove GR, Alpert NM, Cassem EH, Nierenberg AA, Price BH, Mayberg HS, Fischman AJ, Rauch SL
Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for treatment of major depression
J Neurosurg. 2003 Dec;99(6):1010-7


E

El-Khoury AE, Pereira PC, Borgonha S, Basile-Filho A, Beaumier L, Wang SY, Metges CC, Ajami AM, Young VR
Twenty-four-hour oral tracer studies with L-[1-13C]lysine at a low (15 mg • kg-1 • d-1) and intermediate (29 mg • kg-1 • d-1) lysine intake in healthy adults
Am J Clin Nutr. 72:122-30, 2000


F

Fink H, Luppa P, Mayer B, Rosenbrock H, Metzger J, Martyn JA, Blobner M
Systemic inflammation leads to resistance to atracurium without increasing membrane expression of acetylcholine receptors
Anesthesiology. 98 : 82-8, 2003

Fischman AJ, Yu YM, Livni E, Babich JW, Young VR, Alpert NM, Tompkins RG
Muscle protein synthesis by positron-emission tomography with L-[methyl-11C]methionine in adult humans
Proc Natl Acad Sci U S A. 95 :12793-8, 1998

Fischman AJ
Radionuclide imaging probes for expressed proteins
J Nucl Cardiol. 6(4):438-48, 1999

Fischman AJ, Hsu H, Carter EA, Yu YM, Tompkins RG, Guerrero JL, Young VR, Alpert NM
Regional measurement of canine skeletal muscle blood flow by positron emission tomography with H215O
J Appl Physiol 92:1709-16, 2002

Fischman AJ, Thrall JH
Who should read and interpret 18F-FDG PET studies?
J Nucl Med. 2003; 44(8):1197-9

Forslund AH, Hambraeus L, van Beurden H, Holmback U, El-Khoury AE, Hjorth G, Olsson R, Stridsberg M, Wide L, Akerfeldt T, Regan M, Young VR
Inverse relationship between protein intake and plasma free amino acids in healthy men at physical exercise
Am J Physiol Endocrinol Metab. 278:E857-67, 2000

Forslund AH, Hambraeus L, Olsson RM, El-Khoury AE, Yu Y-M, Young VR
The 24-h whole body leucine and urea kinetics at normal and high protein intakes with exercise in healthy adults
Am J Physiol 275: E310-E320, 1998


G


H

Han T, Kim H, Bae J, Kim K, Martyn JA
Neuromuscular pharmacodynamics of rocuronium in patients with major burns
Anesth Analg. 2004 Aug;99(2):386-92

Herndon DN, Tompkins RG
Support of the metabolic response to burn injury
Lancet 2004 Jun 5;363(9424):1895-902

Hirose M, Kaneki M, Sugita H, Yasuhara S, Martyn JA
Immobilization depresses insulin signaling in skeletal muscle
Am J Physiol Endocrinol Metab. 279:E1235-41, 2001

Hirose M, Kaneki M, Sugita H, Yasuhara S, Ibebunjo C, Martyn JA, Iebunjo C
Long-term denervation impairs insulin receptor substrate-1-mediated insulin signaling in skeletal muscle
Metabolism. 50:216-22, 2001

Hirose M, Martyn JA, Kuroda Y, Marunaka Y, Tanaka Y
Mechanism of suppression of insulin signaling with lignocaine
Br J Pharmacol. 136:76-80, 2002

Hu RH, Yu YM, Costa D, Young VR, Ryan CM, Burke JF, Tompkins RG
A rabbit model for metabolic studies after burn injury
J Surg Res. 75 :153-60, 1998


I

Ibebunjo C, Martyn JA
Disparate dysfunction of skeletal muscles located near and distant from burn site in the rat.
J. Muscle & Nerve. 24(10):1283-94, 2001 Oct

Ibebunjo C, Martyn JA
Fiber atrophy, but not changes in acetylcholine receptor expression, contributes to the muscle dysfunction after immobilization
Crit Care Med. 27 :275-85, 1999

Ibebunjo C, Nosek MT, Itani MS, Martyn JA
Mechanisms for the paradoxical resistance to d-tubocurarine during immobilization-induced muscle atrophy
J Pharmacol Exp Ther. 283:443-51, 1997

Ibebunjo C, Martyn JA
Thermal injury induces greater resistance to d-tubocurarine in local rather than in distant muscles in the rat
Anesth Analg. 91:1243-9, 2000

Ikezu T, Okamoto T, Yonezawa K, Tompkins RG, Martyn JA
Analysis of thermal injury-induced insulin resistance in rodents. Implication of postreceptor mechanisms
J Biol Chem. 272 :25289-95, 1997

Ikezu T, Yasuhara S, Granneman JG, Kraemer FB, Okamoto T, Tompkins RG, Martyn JA
A unique mechanism of desensitization to lipolysis mediated by beta3-adrenoceptor in rats with thermal injury
Am J Physiol. 277 :E316-24, 1999


J


K

Kurpad AV, Regan MM, Varalakshmi S, Vasudevan J, Gnanou J, Raj T, Young VR
Daily methionine requirements of healthy Indian men, measured by a 24-h indicator amino acid oxidation and balance technique
Am J Clin Nutr. 2003 May;77(5):1198-205

Kurpad AV, Raj T, El-Khoury A, Kuriyan R, Maruthy K, Borgonha S, Chandukudlu D, Regan MM, Young VR
Daily requirement for and splanchnic uptake of leucine in healthy adult Indians
Am J Clin Nutr. 74(6):747-55, 2001

Kurpad AV, Regan MM, Varalakshmi S, Gnanou J, Young VR
Daily requirement for total sulfur amino acids of chronically undernourished Indian men
Am J Clin Nutr. 2004 Jul;80(1):95-100

Kurpad AV, Regan MM, Nazareth D, Nagaraj S, Gnanou J, Young VR
Intestinal parasites increase the dietary lysine requirement in chronically undernourished Indian men
Am J Clin Nutr. 2003 Dec;78(6):1145-51 (AA)

Kurpad AV, Regan MM, Raj T, Varalakshmi S, Gnanou J, Thankachan P, Young VR
Leucine requirement and splanchnic uptake of leucine in chronically undernourished adult Indian subjects
Am J Clin Nutr. 2003 Apr;77(4):861-7

Kurpad AV, Raj T, El-Khoury A, Beaumier L, Kuriyan R, Srivatsa A, Borgonha S, Selvaraj A, Regan MM, Young VR
Lysine requirements of healthy adult Indian subjects, measured by an indicator amino acid balance technique
Am J Clin Nutr. 73:900-7, 2001

Kurpad AV, Young VR
What is apparent is not always real: lessons from lysine requirement studies in adult humans
J Nutr. 2003 Apr;133(4):1227-30

Kyriakis JM, Avruch J
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
J. Physiol Rev. 2001 Apr;81(2):807-69


L

Lau T, Owen W, Yu YM, Noviski N, Lyons J, Zurakowski D, Tsay R, Ajami A, Young VR, Castillo L
Arginine, citrulline, and nitric oxide metabolism in end-stage renal disease patients
J Clin Invest. 105:1217-25, 2000

Livni E, Berker M, Hillier S, Waller SC, Ogan MD, Discordia RP, Rienhart JK, Rubin RH, Fischman AJ
Preparation and pharmacokinetics of 11C labeled stavudine (d4T)
Nucl Med Biol. 2004 Jul;31(5):613-21

Lohmann R, Souba WW, Zakrzewski K, Bode BP
Stimulation of rat hepatic amino acid transport by burn injury
Metabolism. 47 :608-16, 1998

Louis M, Poortmans JR, Francaux M, Hultman E, Berre J, Boisseau N, Young VR, Smith K, Meier-Augenstein W, Babraj JA, Waddell T, Rennie MJ
Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed states
Am J Physiol 284 :E764-70, 2003

Lydon A, Martyn JA
Apoptosis in critical illness
Int Anesthesiol Clin. 41:65-77, 2003

Lyons J, Rauh-Pfeiffer A, Yu YM, Lu XM, Zurakowski D, Tompkins RG, Ajami AM, Young VR, Castillo L
Blood glutathione synthesis rates in healthy adults receiving a sulfur amino acid-free diet
Proc Natl Acad Sci U S A. 97:5071-6, 2000

Lyons J, Rauh-Pfeiffer A, Ming-Yu Y, Lu XM, Zurakowski D, Curley M, Collier S, Duggan C, Nurko S, Thompson J, Ajami A, Borgonha S, Young VR, Castillo L
Cysteine metabolism and whole blood glutathione synthesis in septic pediatric patients
Crit Care Med. 29:870-7, 2001

Lu XM, Lu MY, Fischman AJ, Tompkins RG
A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro)
J Mass Spectrom. 40(5):599-607, 2005 May

Lu XM, Lu M, Tompkins RG, Fischman AJ
Site-specific detection of S-nitrosylated PKB alpha/Akt1 from rat soleus muscle using CapLC-Q-TOF(micro) mass spectrometry
J Mass Spectrom. 40(9):1140-8, 2005 Sep

M

Martini WZ, Chinkes DL, Pusateri AE, Holcomb JB, Yu YM, Zhang XJ, Wolfe RR
Acute changes in fibrinogen metabolism and coagulation after hemorrhage in pigs
Am J Physiol Endocrinol Metab. 289(5):E930-4, 2005 Nov

Martyn JA, Goudsouzian NG, Chang Y, Szyfelbein SK, Schwartz AE, Patel SS
Neuromuscular effects of mivacurium in 2- to 12-yr-old children with burn injury
Anesthesiology. 92:31-7, 2000

Martyn JA, Vincent A
A new twist to myopathy of critical illness
Anesthesiology. 91(2):337-9, 1999

Metges CC, Petzke KJ, Young VR
Dietary requirements for indispensable amino acids in adult humans: new concepts, methods of estimation, uncertainties and challenges
Ann Nutr Metab. 43:267-76, 1999

Metges CC, El-Khoury AE, Selvaraj AB, Tsay RH, Atkinson A, Regan MM, Bequette BJ, Young VR Kinetics of L-[1-13C]leucine when ingested with free amino acids, unlabeled or intrinsically labeled casein
Am J Physiol Endocrinol Metab. 278:E1000-9, 2000

Metges CC, Yu YM, Cai W, Lu XM, Wong S, Regan MM, Ajami A, Young VR
Oxoproline kinetics and oxoproline urinary excretion during glycine- or sulfur amino acid-free diets in humans
Am J Physiol Endocrinol Metab. 278:E868-76, 2000

Metges CC, Yu YM, Cai W, Lu XM, Wong S, Ajami AM, Young VR
Plasma L-5-oxoproline carbon and nitrogen kinetics in healthy young adults
J Nutr 129 :1998-2004, 1999

Miner SE, Al-Hesayen A, Kelly S, Benson T, Thiessen JJ, Young VR, Parker JD
L-arginine transport in the human coronary and peripheral circulation
Circulation. 2004 Mar 16;109(10):1278-83. Epub 2004 Mar 08

Mokuno Y, Berthiaume F, Tompkins RG, Balis UJ, Yarmush ML
Technique for expanding the donor liver pool: heat shock preconditioning in a rat fatty liver model
Liver Transpl. 2004; 10(2):264-72


N

Nosek MT, Martyn JA
Na+ channel and acetylcholine receptor changes in muscle at sites distant from burns do not simulate denervation
J Appl Physiol. 82 :1333-9, 1997


O


P

Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA
Burn injury causes mitochondrial dysfunction in skeletal muscle
Proc Natl Acad Sci U S A. 102(15):5368-73, 2005 Apr 12.

Pawlik TM, Souba WW, Bode BP
Asparagine uptake in rat hepatocytes: resolution of a paradox and insights into substrate-dependent transporter regulation
Amino Acids. 20:335-52, 2001

Pawlik TM, Carter EA, Bode BP, Fischman AJ, Tompkins RG
Central role of interleukin-6 in burn-induced stimulation of hepatic amino acid transport
Int J Mol Med. 2003 Oct;12(4):541-8

Pawlik TM, Lohmann R, Souba WW, Bode BP
Hepatic glutamine transporter activation in burn injury: role of amino acids and phosphatidylinositol-3-kinase
Am J Physiol 278:G532-41, 2000

Praskova M, Khoklatchev A, Ortiz-Vega S, Avruch J
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras
J. Biochem J. 2004 Jul 15;381(Pt 2):453-62

Prelack K, Dwyer J, Sheridan R, Yu YM, Lydon M, Petras L, Dolnikowski G, Kehayias JJ
Body water in children during recovery from severe burn injury using a combined tracer dilution method
J Burn Care Rehabil. 26(1):67-74, 2005 Jan-Feb.

Prelack K, Sheridan R, Yu YM, Stamatelatos IE, Dwyer J, Dallal GE, Lydon M, Petras L, Kehayias JJ
Sodium bromide by instrumental neutron activation analysis quantifies change in extracellular water space with wound closure in severely burned children
Surgery. 2003 Apr;133(4):396-403


Q


R

Rabizadeh S, Xavier RJ, Ishiguro K, Bernabeortiz J, Lopez-Ilasaca M, Khokhlatchev A, Mollahan P, Pfeifer GP, Avruch J, Seed B
The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death
J Biol Chem. 2004 Jul 9;279(28):29247-54

Raguso CA, Regan MM, Young VR
Cysteine kinetics and oxidation at different intakes of methionine and cysteine in young adults
Am J Clin Nutr. 71:491-9, 2000

Rahme LG, Tan MW, Le L, Wong SM, Tompkins RG, Calderwood SB, Ausubel FM
Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors
Proc Natl Acad Sci USA. 25;94:13245-50, 1997

Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG
Plants and animals share functionally common bacterial virulence factors
Proc Natl Acad Sci U S A. 97:8815-21, 2000

Rand WM, Pellett PL, Young VR
Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults
Am J Clin Nutr. 77:109-27, 2003

Ryan CM, Schoenfeld DA, Thorpe WP, Sheridan RL, Cassem EH, Tompkins RG
Objective estimates of the probability of death from burn injuries
N Engl J Med. 338 :362-6, 1998


S

Schulz JT 3rd, Tompkins RG, Burke JF
Artificial skin
Annu Rev Med. 51:231-44, 2000

Sheridan RL, Morgan JR, Cusick JL, Petras LM, Lydon MM, Tompkins RG
Initial experience with a composite autologous skin substitute
Burns. 27 :421-4, 2001

Sheridan RL, Schulz JT, Ryan CM, Schnitzer JJ, Lawlor D, Driscoll DN, Donelan MB, Tompkins RG
Long-term consequences of toxic epidermal necrolysis in children
Pediatrics. 109:74-8, 2002

Sheridan RL, Hinson MI, Liang MH, Nackel AF, Schoenfeld DA, Ryan CM, Mulligan JL, Tompkins RG
Long-term outcome of children surviving massive burns
JAMA 283:69-73, 2000

Sheridan RL, Prelack K, Yu YM, Lydon M, Petras L, Young VR, Tompkins RG
Short-term enteral glutamine does not enhance protein accretion in burned children: a stable isotope study
Surgery. 2004 Jun;135(6):671-8

Sheridan RL, Tompkins RG
What's new in burns and metabolism?
J Am Coll Surg. 2004 Feb;198(2):243-63

Shin LM, Shin PS, Heckers S, Krangel TS, Macklin ML, Orr SP, Lasko N, Segal E, Makris N, Richert K, Levering J, Schacter DL, Alpert NM, Fischman AJ, Pitman RK, Rauch SL
Hippocampal function in posttraumatic stress disorder
Hippocampus. 2004;14(3):292-300

Shin YS, Fink H, Khiroya R, Ibebunjo C, Martyn J
Prednisolone-induced muscle dysfunction is caused more by atrophy than by altered acetylcholine receptor expression
Anesth Analg. 91:322-8, 2000

Smith HK, Maxwell L, Martyn JA, Bass JJ
Nuclear DNA fragmentation and morphological alterations in adult rabbit skeletal muscle after short-term immobilization
Cell Tissue Res. 302:235-41, 2000

Spiller MP, Kambadur R, Jeanplong F, Thomas M, Martyn JK, Bass JJ, Sharma M
The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD
Mol Cell Biol.
22:7066-82, 2002

Sugita H, Kaneki M, Sugita M, Yasukawa T, Yasuhara S, Martyn JA
Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle
Am J Physiol Endocrinol Metab. 288(3):E585-91, 2005 Mar.

Sugita H, Fujimoto M, Yasukawa T, Shimizu N, Sugita M, Yasuhara S, Martyn JA, Kaneki M
Inducible nitric-oxide synthase and NO donor induce insulin receptor substrate-1 degradation in skeletal muscle cells
J Biol Chem. 280(14):14203-11, 2005 Apr 8.

Sugita H, Kaneki M, Tokunaga E, Sugita M, Koike C, Yasuhara S, Tompkins RG, Martyn JA
Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance
Am J Physiol Endocrinol Metab. 282:E386-94, 2002


T

Takabayashi T, Vannier E, Burke JF, Tompkins RG, Gelfand JA, Clark BD
Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells
J Infect Dis. 177 :1622-8, 1998

Tan MW, Rahme LG, Sternberg JA, Tompkins RG, Ausubel FM
Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors
Proc Natl Acad Sci U S A. 96 :2408-13, 1999

Tawakol A, Forgione MA, Stuehlinger M, Alpert NM, Cooke JP, Loscalzo J, Fischman AJ, Creager MA, Gewirtz H
Homocysteine impairs coronary microvascular dilator function in humans
J Am Coll Cardiol. 40:1051-58, 2002

Tawakol A, Sims K, MacRae C, Friedman JR, Alpert NM, Fischman AJ, Gewirtz H
Myocardial flow regulation in people with mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes/myoclonic epilepsy and ragged red fibers and other mitochondrial syndromes
Coron Artery Dis. 14 :197-205, 2003

Tompkins RG
Presidential Address - The American Burn Association in the New Millennium
J Burn Care Rehabil. 22:369-374, 2001

Tredget EE, Yu Y-M. In: Lorente JA, Esteban A. eds.
Efectos metabólicos del trauma y el traumatismo térmico: implicaciones en las necesidades calóricas
Cuidados intensivos del paciente quemado Barcelona: Spinger-Verlag Ibérica 1998; pp. 199-234


U


V

Vogt JA, Yarmush DM, Yu YM, Zupke C, Fischman AJ, Tompkins RG, Burke JF
TCA cycle flux estimates from NMR- and GC-MS-determined [13C]glutamate isotopomers in liver
Am J Physiol. 272 :C2049-62, 1997


W

Werner J, Saghir M, Warshaw AL, Lewandrowski KB, Laposata M, Iozzo RV, Carter EA, Schatz RJ, Fernandez-Del Castillo C
Alcoholic pancreatitis in rats: injury from nonoxidative metabolites of ethanol
Am J Physiol Gastrointest Liver Physiol. 283:G65-73, 2002


X

Xu J, Fei Z, Yu YM, Xu W, Rhodes A, Tompkins RG, Schulz JT
In vivo rabbit hindquarter model for assessment of regional burn hypermetabolism
J Appl Physiol. 94 :135-40, 2003


Y

Yarmush DM, MacDonald AD, Foy BD, Berthiaume F, Tompkins RG, Yarmush ML
Cutaneous burn injury alters relative tricarboxylic acid cycle fluxes in rat liver
J Burn Care Rehabil. 20(4):292-302, 1999.

Yasuhara S, Kaneki M, Sugita H, Sugita M, Asai A, Sahani N, Chon JY, Tompkins RG, Martyn JA
Adipocyte apoptosis after burn injury is associated with altered fat metabolism
J Burn Care Res. 27(3):367-76, 2006 May-Jun.

Yasuhara S, Kanakubo E, Perez ME, Kaneki M, Fujita T, Okamoto T, Martyn JA
Burn injury induces skeletal muscle apoptosis and the activation of caspase pathways in rats
The 1999 Moyer award. J Burn Care Rehabil. 20 :462-70, 1999

Yasuhara S, Perez ME, Kanakubo E, Yasuhara Y, Shin YS, Kaneki M, Fujita T, Martyn JA
Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals
Am J Physiol Endocrinol Metab. 279:E1114-21, 2001

Yasukawa T, Tokunaga E, Ota H. Sugita H, Martyn JA, Kaneki M
S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance
J Biol Chem. 280(9):7511-8, 2005 Mar 4.

Yasukawa T, Kaneki M, Yasuhara S, Lee SL, Martyn JA
Steroidal nondepolarizing muscle relaxants do not simulate the effects of glucocorticoids on glucocorticoid receptor-mediated transcription in cultured skeletal muscle cells
Anesthesiology. 2004 Jun;100(6):1615-9

Yokoyama T, Banta S, Berthiaume F, Nagrath D, Tompkins RG, Yarmush ML
Evolution of intrahepatic carbon, nitrogen, and energy metabolism in a D-galactosamine-induced rat liver failure model
Metab Eng. 7(2):88-103, 2005 Mar.

Young VR, Ajami AM
Glutamate: an amino acid of particular distinction
J Nutr. 130(4S Suppl):892S-900S, 2000

Young VR, Ajami AM
Glutamine: the emperor or his clothes?
J Nutr 131(9 Suppl):2449S-59S, 2001

Young VR
Got some amino acids to spare?
Am J Clin Nutr. 74:709-11, 2001

Young VR, Ajami AM
Metabolism 2000: the emperor needs new clothes
Proc Nutr Soc. 60:27-44, 2001

Young VR, Borgonha S
Nitrogen and amino acid requirements: the Massachusetts Institute of Technology amino acid requirement pattern
J Nutr. 130:1841S-9S, 2000

Young VR, Yu YM, Borgonha S
Proteins, peptides and amino acids in enteral nutrition: overview and some research challenges
Nestle Nutr Workshop Ser Clin Perform Programme. 3:1-20; discussion 20-3, 2000

Young VR, El-Khoury AE, Raguso CA, Forslund AH, Hambraeus L
Rates of urea production and hydrolysis and leucine oxidation change linearly over widely varying protein intakes in healthy adults
J Nutr. 130:761-6, 2000

Young VR, Borgonha S, Ajami AM
Trends in tracer techniques, including use of positron emission tomography
Diabetes Nutr Metab. 13:35-45, 2000

Yu YM, Ryan CM, Castillo L, Lu XM, Beaumier L, Tompkins RG, Young VR
Arginine and ornithine kinetics in severely burned patients: increased rate of arginine disposal
Am J Physiol Endocrinol Metab. 280:E509-17, 2001

Yu YM, Tompkins RG, Ryan CM, Young VR
The metabolic basis of the increase of the increase in energy expenditure in severely burned patients
JPEN 23:160-8, 1999

Yu YM, Ryan CM, Fei ZW, Lu XM, Castillo L, Schulz JT, Tompkins RG, Young VR
Plasma L-5-oxoproline kinetics and whole blood glutathione synthesis rates in severely burned adult humans
American Journal of Physiology-Endocrinology & Metabolism. 282:E247-58, 2002

Yu Y-M, Ryan CM, Cai W
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