The MGH Burn Research Center depends heavily not only on having highly-qualified
scientists with long experience in their respective fields, but also
on having state-of-the-art equipment in highly-specialized laboratories.
The Massachusetts General Hospital is fortunate to be a world leader
in laboratory facilities and in its collaborations with Boston Children's Hospital
and the Stanford Genome Technology Center.
Each principal investigator has individual laboratory facilities where
the major portions of his or her work are performed. These laboratories
are well equipped for routine as well as specialized experimental
much of the major equipment is located in individual laboratories,
the long-term and close association of the Center investigators
allows the investigators to take advantage of unique or highly specialized
equipment as it becomes available at the collaborating institutions.
This organizational synergy in sharing resources is exemplified
in many ways.
It is from our longstanding and successful collaborations with
Dr. Ronald Davis' laboratory at the Stanford Genome Technology Center
that we are able to bring our scientific environment in genomics technologies
and computational analysis to our new Center. The Genome Center in
Palo Alto, California offers us unparalleled resources including
next-generation sequencers, robotics, oligonucleotide synthesis, and computational servers.
As a natural evolution of our Center, we have recruited Morris White at
Boston Children's Hospital, an international expert in the regulation of
several molecules involved in dysregulated insulin receptor signaling
and mitochondrial dysfunction. Children's Hospital brings exceptional
tools to our Center including unique knockin/knockout technologies to
create transgenic murine models highly relevant to our research as
well as a library of 25 antibodies of interest.